Conan & Liza: A Love Story From Late Night To Forever!

Ever wondered about the woman who captured the heart of one of comedy's most beloved figures? Liza Powel O'Brien isn't just the wife of Conan O'Brien; she's a force in her own right, a talented writer, playwright, and podcast host who has carved her own path while supporting her husband's stellar career.

Their story began like something out of a romantic comedy. In 2000, Liza Powel, then a copywriter for the advertising agency Foote, Cone & Belding, found herself on the set of "Late Night with Conan O'Brien." Conan was filming a skit, and as he later confessed to Piers Morgan, it was love at first sight quite literally. He described the moment as, "somewhere, in the vault at NBC, theres footage of me literally falling for my wife on camera." It was an unexpected beginning to a relationship that would blossom into a marriage of over two decades and a partnership that continues to thrive.

Liza grew up in Washington, D.C., the daughter of Jake and Pamela Powel. Her academic pursuits led her to Vassar College, where she earned a bachelor's degree. She later pursued her passion for writing, obtaining an MFA in fiction writing from Columbia University's School of the Arts. This dedication to her craft has allowed her to excel in various creative fields.

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The couple's journey from that fateful meeting in 2000 to their wedding on January 12, 2002, at St. James Cathedral in Seattle, Washington, is a testament to their deep connection. After dating for 18 months, they sealed their commitment in a private ceremony surrounded by loved ones. Their family expanded with the arrival of their daughter, Neve, in 2003, followed by their son, Beckett, in 2005. Family life has always been a priority for both Conan and Liza.

While she is perhaps most widely recognized as the wife of the renowned comedian, Liza Powel O'Brien has established herself as a talented and accomplished individual in her own right. Her background as a copywriter at Foote, Cone & Belding honed her skills in crafting compelling narratives and understanding audience engagement, abilities that she has successfully translated into her playwriting and podcasting ventures.

Liza's foray into playwriting has garnered considerable attention. She has penned over a dozen plays, showcasing her unique voice and perspective. Titles like "Apostrophe," "The Great Experiment," and "Ruthie Goes Shopping" offer a glimpse into the diverse themes and characters that populate her theatrical world. Her work has been showcased at prestigious venues such as the Geffen Playhouse, Echo Theater Company, The Blank Theatre, Unscreened LA, Naked Angels LA, Ojai Playwrights Conference, Tennessee Williams & New Orleans Literary Festival, Hedgebrook, and Whidbey Island Center for the Arts. She even issued a "production alert!" on June 10, 2022, inviting people to visit Whidbey Island to see "Apostrophe," and shared a link for access to Echo Theatre's Labfest 2022, expressing her excitement to be part of the group.

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Adding another dimension to her creative portfolio, Liza Powel O'Brien is the narrator and writer behind the "Significant Others" podcast. This fascinating non-fiction series delves into the lives of individuals who often remain in the shadows of history the spouses, partners, and companions of famous figures. In an appearance on her husband's podcast, "Conan O'Brien Needs a Friend," Liza described the podcast as a deeper exploration of these untold stories, shedding light on the often-overlooked contributions and experiences of those who stood beside iconic personalities.

The bond between Conan and Liza is evident in their public appearances and in the way they speak about each other. Conan, never one to shy away from humor, often incorporates anecdotes about their life together into his comedic routines. However, beneath the jokes lies a genuine affection and respect. In 2020, while appearing on Michelle Obama's podcast, Conan spoke about their marriage, highlighting Liza as the "perfect person for me." This sentiment reflects the deep understanding and mutual support that characterizes their relationship.

Their presence at high-profile events further underscores their partnership. Whether it's attending the 2000 New York Film Critics Circle Awards, gracing the 2016 Vanity Fair Oscar Party in Beverly Hills, California, or celebrating Conan's achievements at the Kennedy Center Mark Twain Prize for American Humor, Liza has consistently been by Conan's side. She was there on August 27, 2006, at the Governor's Ball after the 58th Annual Primetime Emmy Awards at the Shrine Auditorium in Los Angeles. Her unwavering support was particularly evident when Conan received the prestigious Mark Twain Prize for American Humor in 2025; and when his Max TV series "Conan O'Brien Must Go" won a 2024 Creative Arts Emmy Award for outstanding writing for a nonfiction program, he made sure to thank Liza for her constant support.

The couple also shares a passion for family and are often seen attending events with their children. They were spotted at a basketball game between the Houston Rockets and the Los Angeles Clippers on January 18, 2016, in Los Angeles, and at the Hammer Museum K.A.M.P. on May 18, 2014, also in Los Angeles. These moments offer glimpses into their life as a family, balancing their careers with raising their children.

Liza Powel O'Brien's career is a testament to her diverse talents and unwavering dedication. From her early days as a copywriter to her success as a playwright and podcaster, she has consistently demonstrated her creative prowess. Her involvement in projects like "Significant Others" showcases her commitment to exploring untold stories and giving voice to those who are often overlooked. Her work in theater speaks to her ability to craft compelling narratives and engage audiences on a deeply emotional level.

Conan O'Brien, on the other hand, has enjoyed a remarkable career in television, solidifying his place as one of the most influential figures in comedy. His contributions to iconic shows like "The Simpsons," "Saturday Night Live," and "Late Night with Conan O'Brien" have earned him widespread acclaim and a devoted following. In 2025, he took on the prestigious role of hosting the Academy Awards, further cementing his status as a leading figure in the entertainment industry.

Their enduring marriage, spanning over two decades, is a testament to their compatibility and commitment. They met in 2000, and after dating for 18 months, they married in 2002. They have built a life together, raising two children and supporting each other's professional endeavors. This year, 2025, marks their 25th anniversary, a significant milestone in their journey as a couple. Conan has consistently praised Liza for her intelligence, humor, and unwavering support, often referring to her as his "perfect person." He joined Michelle Obamas podcast in 2020 to discuss their marriage.

The success of Liza's "Significant Others" podcast demonstrates her ability to connect with audiences on a personal level. The podcast delves into the lives of those who often remain in the shadows, highlighting their contributions and experiences. Through her insightful storytelling and engaging narration, Liza brings these untold stories to life, offering listeners a fresh perspective on historical events and figures. Conan's "Team Coco" platform has been instrumental in promoting Liza's podcast, further showcasing his support for her work.

Moreover, Liza's work extends beyond her podcast and playwriting endeavors. Her involvement in various theatrical productions and workshops, including the Ojai Playwrights Conference and the Tennessee Williams & New Orleans Literary Festival, reflects her dedication to nurturing the art of storytelling and fostering collaboration among artists. Her participation in these events underscores her commitment to supporting the creative community and promoting artistic expression.

Liza Powel O'Brien's journey is a compelling narrative of personal and professional fulfillment. She has successfully balanced her role as a wife and mother with her passion for writing and storytelling. Her accomplishments in playwriting, podcasting, and other creative endeavors have established her as a respected voice in the arts and entertainment industry. Her story serves as an inspiration to aspiring writers and artists, demonstrating the power of dedication, creativity, and unwavering self-belief.

As Conan O'Brien prepares for his future endeavors, including potentially hosting the Oscars, he can undoubtedly rely on the unwavering support of his wife, Liza Powel O'Brien. Their partnership, built on love, respect, and mutual admiration, will continue to be a source of strength and inspiration for both of them as they navigate the challenges and triumphs of their respective careers.

Liza Powel O'Brien, born under the zodiac sign Scorpio on November 12, 1970, continues to inspire with her creative endeavors and her dedication to family and community. Her journey is a testament to the power of pursuing one's passions and embracing the unexpected opportunities that life presents. Her contributions to the arts and entertainment industry, coupled with her unwavering support for her husband and children, make her a truly remarkable individual.

The images capturing Conan O'Brien and Liza Powel at various events throughout their relationship offer a glimpse into their shared life and enduring bond. From the early days of their courtship at the 2000 New York Film Critics Circle Awards to their glamorous appearance at the 2016 Vanity Fair Oscar Party, these photographs document their journey as a couple. The images also showcase their family life, with snapshots of them attending basketball games and museum events with their children, Neve and Beckett. These visual representations of their life together offer a poignant reminder of the importance of love, family, and mutual support in navigating the complexities of life and career.